Biostatistics Tool · v4.1

Sample Size Calculator

Community Medicine & Public Health · KSHEMA · Dr. Pawan Kumar B

Sample Size Calculation Sheet

Result
Minimum Sample Size
—
participants
Finite Population CorrectionFPC
Apply FPCoff
Known finite population
FPC-adjusted n
—
Cluster Design EffectDEFF
Apply DEFFoff
Subjects per cluster
0.05
Community ≈ 0.02–0.10
DEFF-adjusted n
—
OR / RR → P₁ ConverterOR/RR
Derive P₁ from OR or RR for Two Proportions
Derived P₁
—
Comparative Table
Pilot Study Sizing Estimate parameters before the main study
Prevalence Estimation Pilot
10%
—
Assumes P=50% (worst case)
SD Estimation Pilot
15%
—
Precision-based; minimum n ≥ 30
10% of Main Study
Standard: pilot = 10% of main n, minimum 30
—
Based on current main study n
Feasibility Pilot
Logistics / instrument testing — not powered for significance
12–30
CONSORT/SPIRIT recommendation
Study References
Multi-Outcome Sample Size Enter up to 5 outcomes — tool picks the largest n
Protocol Wizard Guided formula selection and parameter entry
Saved Presets Save and reload study configurations
v4.1 Formulas: Cochran (1977) proportions · FPC: n/(1+(n−1)/N) · DEFF: 1+(m−1)ρ · Schlesselman (1982) case-control · Buderer (1996) diagnostics · Kish (1965) cluster · Donner (1992) kappa · Lemeshow (1990) means · All two-tailed. Cross-verify with OpenEpi or nMaster before submission.